Research has shown that titanium particles may occur in inflamed tissues around dental implants. But a new study, published in Communications Medicine, showed that titanium micro-particles are found at all examined implants, with or without signs of inflammation.
Tord Berglundh, senior professor of periodontology at Sahlgrenska Academy, University of Gothenburg, told Medical Xpress that titanium is a “well-studied material that has been used for decades.”
“It is biocompatible and safe, but our findings show that we need to better understand what happens to the micro-particles over time. Do they remain in the tissue or spread elsewhere in the body?” said Berglundh.
After analyzing samples of human soft tissue taken from implant sites with and without peri-implantitis, the study by the University of Gothenburg and Uppsala University also identified 14 genes that may be affected by these particles.
“But it is unclear whether the particles influence the local immune response or if the difference in gene expression reflects inter-individual variability in inflammatory conditions,” says Carlotta Dionigi, specialist in periodontology and researcher at the Department of Periodontology, Sahlgrenska Academy, University of Gothenburg.
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